Cite This Article. By using standard restriction fragment length polymorphism, 6 zero-copy IS Mycobacterium tuberculosis isolates were identified from 1, Maryland isolates as part of the National Tuberculosis Genotyping Surveillance Network Project. By using various genotyping methods, we demonstrated that this zero band cluster can be differentiated into six genotypes. IS restriction fragment length polymorphism RFLP has been used to investigate Mycobacterium tuberculosis transmission within populations since the early s 1 — 4. However, some strains do not have any IS insertions and thus are zero-band strains 5 and are considered a single IS cluster by exclusion 5 , 6. These zero-band strains are rare in the United States and usually are found in persons from Southeast Asia.
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Cite This Article. Of patients with TB, those with HIV infection differed from those without known HIV infection in having more frequent prior exposure to clinical services and more frequent previous TB therapy or prophylaxis. MDR-TB has been associated with inadequate treatment regimens, poor adherence to treatment, poorly managed TB-control programs, and unenforced hospital infection control programs, as well as HIV infection 2.